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Technical Program
Jack Henion, Ph.D.
Co-Founder and CSO, Advion, Inc.
Emeritus Professor, Cornell University
“The Evolution of Today’s LC/MS Techniques Followed by an Example of Application to Breath Analysis for THC”
This presentation will summarize how LC/MS techniques evolved from the Direct Liquid Introduction (DLI), Particle Beam and Thermospray approaches based upon the above. The early techniques were replaced by creating gas-phase ions at atmospheric pressure and introducing them into the ion optics of an atmospheric pressure ionization (API) mass spectrometer via atmospheric pressure chemical ionization (APCI) or electrospray ionization (ESI). These two latter ionization techniques have revolutionized the means of doing LC/MS across a wide array of modern mass spectrometer technologies ranging from simple benchtop single quadrupoles (LC/MS), to tandem triple quadrupoles (LC/MS/MS), quadrupole/time of flight (LC/QTOF) and orbitrap mass spectrometers with high mass resolution. A variety of interesting applications will be shown along with some recent research to develop a breath analysis technique amenable to a mobile laboratory for roadside breath analysis for marijuana using a single quadrupole LC/MS system.
Attend In-Person
The monthly meeting will be held in the Power Center Ballroom, Duquesne University. Registration for dinner is required.
Please pay for your meal with a credit card at the time of the meeting.
$5 for students; $15 for all others.
6:00 pm – Dinner
6:45 pm – Business Meeting
7:30 pm – Technical Program
Attend Virtually
The monthly meeting Technical Program is accessible via the Zoom platform.
Pre-registration required. Link will be emailed.
6:45 pm – Business Meeting
7:30 pm – Technical Program
Please Note: No Parking Before 5:00 PM
There are new Duquesne University parking restrictions now in effect.
- Entry only AFTER 5:00 pm for all members, staff, students, and guests using the Forbes Avenue garage.
- Entry before 5:00 pm is limited to ONLY those involved with set-up in the Powers Center.
- Bring the QR parking ticket to the meeting for a paid QR ticket to scan when leaving the garage.
- The dinner registration form will ask you to indicate if you require a parking pass. Please note: passes are non-refundable and only valid for that meeting.
About the Program Speaker
Professor Jack Henion is Emeritus Professor of Toxicology at Cornell University where he was a member of the College of Veterinary Medicine commencing in 1976. Dr. Henion was co-founder of Advion BioSciences in 1993 where he served as President and CEO until 2006 when he became CSO of Advion, Inc. Professor Henion has received three Doctor Honoris Causa (Honorary Doctorate) degrees in recognition of his international reputation in modern analytical techniques. These were awarded by the University of Ghent, Uppsala University and Albany University. Professor Henion’s Cornell research explored applications in many areas of liquid chromatography/mass spectrometry (LC/MS) employing atmospheric pressure ionization (API) sources. Professor Henion has published 235 peer-reviewed papers, trained over 100 students, post-doctoral scientists, and trainees and received 12 patents for inventions developed from his work. He has also received a number of awards which recognize his contributions to analytical chemistry and entrepreneurship. In December 2019 Dr. Henion retired from Advion, Inc. and is now a consultant on behalf of Henion Enterprises. In June, 2025 Dr. Henion received the ASMS John B. Fenn award for Distinguished Contributions to Mass Spectrometry and also received an award as an inaugural Fellow of ASMS.