Host Your Own Virtual Meeting
Grants are available for institutions that broadcast our Technical Program.
Technical Program
Prof. Daniel W. Armstrong
Welch Distinguished Professor of Chemistry and Biochemistry
University of Texas at Arlington
“Analysis & Ramifications of D-Amino Acids and Peptide Epimers in Biological Systems”
Investigations on the occurrence and biochemical roles of free D-amino acids, as well as D-amino acids containing peptides and proteins in living systems have increased in frequency and significance. (1-3) We now understand some of the biosynthetic and regulatory pathways involved in the occurrence and roles of D-amino acids and peptides epimers in human neurologic diseases and cancer. Peptide epimers have the same exact mass as their all L-AA counterparts making identification and analysis difficult. (4) Also the fact that they are rare and are in complex biological matrices further complicates the situation. In the realm of post-transitional modifications (PTMs) of peptide/protein, epimerization is rarely considered. We show that this can play a profound role in further PTMs and in subsequent peptide/protein function. Effects on kinase and glycosylase function are illustrated and discussed.
Attend In-Person
The monthly meeting will be held in the Power Center Ballroom, Duquesne University. Registration for dinner is required.
Please pay for your meal with a credit card at the time of the meeting.
$5 for students; $15 for all others.
6:00 pm – Dinner
6:45 pm – Business Meeting
7:15 pm – Technical Program
Attend Virtually
The monthly meeting Technical Program is accessible via the Zoom platform.
Pre-registration required. Link will be emailed.
6:45 pm – Business Meeting
7:15 pm – Technical Program
PARKING: Duquesne University Parking Garage entrance is on Forbes Avenue. The Power Center can be accessed from the 8th Floor of the Forbes Garage. Bring your parking ticket to the dinner or meeting for a validation sticker.If there is a special event, please note that you are there for the SACP/SSP meeting.
About the Program Speaker
Daniel W. Armstrong is the Welch Distinguished Professor of Chemistry and Biochemistry at the University of Texas at Arlington. He has > 800 publications and received over 35 awards for teaching and research, including numerous ACS Awards, the Chirality Medal and the Pittsburgh Analytical Chemistry Award. He has been named one of the top 10 analytical scientists in the world by Analytical Scientist magazine and was elected to the National Academy of Inventers in 2014. He has mentored and graduated over 120 Ph.D. analytical chemists. Dr. Armstrong developed the most comprehensive solvation and characterization models for room temperature ionic liquids (RTILs) and pioneered their use in analytical chemistry. He also developed ILs as the most versatile MS reagents. His work was significantly responsible for the chromatography–led revolution in chiral separations. He has developed the field of D-Amino Acids in biological systems. He has developed rapid, high efficiency, microfluidic methods for analyzing microorganisms.