Monthly Meeting

Next meeting:

Wednesday, April 26

Host Your Own Virtual Meeting

Grants are available for institutions that broadcast our Technical Program.

Technical Program

Milton L. Lee

Axcend Corporation and Brigham Young University

Read Full Bio

“Green Liquid Chromatography”

The global high performance liquid chromatography (HPLC) market is the largest among the chromatographic techniques currently over $4 billion USD annually with additional mobile phase solvent purchase/handling/disposal costs approaching $1 billion USD. From a “green” perspective, reduction in use of solvents and electrical power by chromatographers is necessary to do our part to protect the environment and conserve our natural resources as the HPLC market continues to grow.

The ACS’s Green Chemistry Institute has prepared an on-line Analytical Method Greenness Score (AMGS) calculator for LC. Using this calculator and comparing solvent waste reduction plus instrument energy reduction between conventional LC and capillary LC, the AMGS score for capillary LC is over 150 times greener. Considering the number of liquid chromatographs worldwide, switching to more compact LC instrumentation would be a significant contribution to the protection of the environment and conservation of valuable non-renewable resources.

Using capillary columns with small diameter (<0.3 mm i.d.), LC mobile phase flow rates are much lower, pumps are smaller, and the overall instrument size and cost can be significantly reduced. Recently, I have been involved in the development of a novel compact capillary LC that has a small footprint, weighs only 5.4 kg, produces consistent nL to L flowrates at pressures up to 1500 bar, utilizes on-column or miniature flow cell optical UV detection, and is very easy to operate. Compactness allows the LC instrument to be easily moved to wherever it is needed, such as to a sample source, to a bench in the laboratory next door, or to another analytical instrument for easy interfacing.

Attend In-Person

The monthly meeting will be held in the Power Center Ballroom, Duquesne University. Registration for dinner is required.


5:30 PM – 6:30 PM – Social Hour
6:30 PM – 7:15 PM – Dinner
7:15 PM – 8:00 PM – Intro of Former Chairs + Business Meeting
8:00 PM – Technical Program

Attend Virtually

The monthly meeting. Technology Forum, and Technical Program are accessible via the Zoom platform.

Pre-registration required. Link will be emailed.
7:15 PM – Business Meeting
8:00 PM – Technical Program

PARKING: Duquesne University Parking Garage entrance is on Forbes Avenue. The Power Center can be accessed from the 8th Floor of the Forbes Garage. Bring your parking ticket to the dinner or meeting for a validation sticker.If there is a special event, please note that you are there for the SACP/SSP meeting.

About the Program Speaker

Milton L. Lee received a B.A. Degree in Chemistry from the University of Utah and a Ph.D. in Analytical Chemistry from Indiana University. He was a postdoctoral researcher at MIT before accepting a faculty position at Brigham Young University. Dr. Lee’s research centers on capillary separation techniques and mass spectrometry detection. He has co-authored over 600 publications and has received various awards including the ACS Award in Chromatography, ACS Award in Chemical Instrumentation, Pittsburgh Analytical Chemistry Award, ACS Award in Separations Science and Technology both LCGC Europe and North America Lifetime Achievement Awards, and the 2019 ACS Award in Analytical Chemistry. Dr. Lee has mentored over 100 graduate students and post-doctoral researchers. Professor Lee is also an entrepreneur and has been involved in transferring technology from his university research laboratory to the private sector, co founding four analytical instrument companies. He was named five times on the Analytical Scientist Power List, the latest in 2021.